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Organic Control

The path tests


The patch tests (skin contact allergy tests) were first demonstrated by Professor Josef Jadassohn in 1896 as a diagnostic technique for allergic contact dermatitis.

Currently, patch tests are used for Contact Dermatitis (CD) and Atopic Dermatitis (AD) for the diagnosis of a specific contact agent. Patch testing is especially important in case of suspected occupational irritant and allergic CD.

Other indications for testing are: skin irritation after topically applied medications, including cosmetic products, personal care products and other products that are in constant contact with human skin.

Testing technology:

The method comprises applying an antigen (allergen) to the skin on a bandage (strips) in standardized concentrations.

tests

You can see on the image below how chemical compound in a reasonable concentration is applied to the hypoallergenic carrier (plaster).

applying-plaster

The plaster is applied to a cleansed skin on sensitive area (carpal, popliteal).

applying-skin

Evaluation
The initial evaluation to be made 15 minutes after the application. Skin is examined 15 minutes after the patch test removal.

result

Next evaluation to be made 24 hours after the application, then in 3 or 4 days, and in some cases – after 7 days.

 

Test results evaluation:
1 pointthe product has a high safety level
2 pointsthe product is considered safe
 3 and 4 pointsthe product has not passed the test and is unsafe for use
These tests are conducted on 20-50 volunteers for determination of cumulative toxicity factor

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